You may run it on a single machine. Some tools like ThinApp or Cameyo can repackage licensed software into portables — but doing so may violate Adobe’s EULA.
While Adobe Photoshop CC 2014 (version 15.2.1) is a legitimate legacy version of Adobe's professional image editing software, the specific "portable" version mentioned (v1521257 Nov 2014) is an unauthorized, modded variant not officially released or supported by Understanding Portable Software Versions adobe photoshop cc 2014 v1521257 nov 2014 portable verified
, represents a refined build within that cycle, often bundled in "portable" formats that allow the software to run from a USB drive without a standard installation. Key Features of CC 2014 (v15.x) Creative Cloud Integration You may run it on a single machine