For users who prefer running ISE directly without a VM, you must use the original "Windows 7/XP" installer and apply compatibility fixes to prevent crashes when opening file dialogs. :
: Perform these same steps in the directory C:\Xilinx\14.7\ISE_DS\common\lib\nt64 . Troubleshooting Common Issues Downloads - AMD xilinx ise 147 windows 10
D. VC2008 runtime warning fix