While it's technically possible to delete the Global Shader Cache-pc-d3d-sm4.bin file, doing so may lead to performance issues in games and graphics applications until the cache is rebuilt.

If the file is legitimately missing from a fresh install, your game launcher can redownload it safely. Global Shader Cache is missing. UE4.3 - Platform & Builds

Are you trying to resolve a specific error message or performance issue?

, as these are often unreliable or contain malware. Instead, use the following official methods to regenerate or restore it: Verify Game Files (Recommended) This is the most effective way to restore missing files without a full download. : Right-click the game in your Library > Properties Installed Files Verify integrity of game files Epic Games : Click the three dots (...) next to the game > Update or Reinstall DirectX