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SSRIs (like Fluoxetine) are often used for separation anxiety or compulsive licking.

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| Drug | Use in Animals | Key Notes | |------|----------------|------------| | Fluoxetine (Reconcile®) | Canine separation anxiety, compulsive disorders | 4–6 weeks to effect | | Clomipramine (Clomicalm®) | Generalized anxiety, OCD in dogs/cats | Monitor for sedation | | Trazodone | Situational anxiety (vet visits, fireworks) | Short-acting, combine with training | | Gabapentin | Chronic pain + anxiety (esp. cats) | Excellent for fear-free vet prep | | Alprazolam | Panic disorders, thunderstorm phobia | Risk of disinhibition aggression | SSRIs (like Fluoxetine) are often used for separation