winetricks winecfg
/opt/ToonBoom/Harmony_20/bin/SceneInfoRenderer \ -scene /path/to/scene.xstage \ -output /render/output.mov \ -width 1920 -height 1080 toon boom harmony linux install
Any specific you're worried about (like a specific GPU or tablet) Installing Harmony on GNU/Linux - Toon Boom Documentation which means more compatibility work.
Fedora is cutting-edge, which means more compatibility work. toon boom harmony linux install