The term translates roughly to "The Three Hundred Verses of Enemy Destruction." While the Kanda Shasti Kavasam is widely known for protection, the Shatru Samhara Trishati is a more advanced stotra focused specifically on neutralizing negativity and defeating enemies (both internal and external). It is believed that reciting these 300 names with devotion invokes the fierce aspect of Lord Murugan, who wields the Vel (divine spear) to vanquish ignorance and adversity.

tithi days (the sixth lunar day), which are particularly sacred to Lord Muruga. Satru Samhara Trishati Homa Purnahuti Mantras (Book)

It is believed to remove evil eye dosha , curses, and the malefic effects of planets, particularly Mars (Angaraka).